BDBM191598 2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acid (KDM5-C49)::KDM5-C49::KDOAM-20
SMILES CCN(CCN(C)C)C(=O)CNCc1cc(ccn1)C(O)=O
InChI Key InChIKey=RGGMVQDDHDCRDM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 191598
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of KDM6B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human C-terminal FLAG-tagged KDM6B (1043 residues) expressed in baculovirus infected sf9 cells using H3K27me3 as substrate preincubated...More data for this Ligand-Target Pair